A man wearing a hospital gown vanished from the car park of Royal Alexandra Hospital in Paisley.
Frazer Duncan was last spotted heading from the car park onto Corsebar Road at 10.04pm on Wednesday.
He has been described at 5ft 10in, with a slim build, brown hair and a long beard.
At the time of his disappearance, he was wearing a hospital gown with grey/blue joggers and red/beige socks or slippers.
Officers said that Frazer frequents the Irvine area, but is also known to travel the central belt and possibly sleep rough in Glasgow.
He has no known connections in Paisley.
Anyone with information is asked to contact Police Scotland on 101 quoting incident number 4381 of July 20, 2022.