Scotland and Edinburgh winger Darcy Graham has been ruled out until February because of a knee injury.
Graham suffered medial ligament damage during his club’s defeat by Munster on Saturday.
Edinburgh have confirmed he will miss the club’s festive fixtures against Glasgow and is “expected to be sidelined until February”.
Graham will be a major doubt for the start of the Guinness Six Nations. Scotland kick off their campaign against England on February 4 before hosting Wales seven days later and then taking on France in Paris on February 26.
The 25-year-old will also miss Edinburgh’s Heineken Champions Cup pool campaign, which starts against Saracens in London on Sunday.
Graham’s medium-term absence will be a major blow for club and country – he has scored 13 tries in 10 matches this season.