A woman has died following a two car crash on the A75.
The 55-year-old was pronounced dead at the scene of the incident that took place near Annan in Dumfries and Galloway.
A 52-year-old man has been left seriously injured following the collision involving a grey Volkswagen Golf and a white Nissan Qashqai.
Emergency services attended after the crash was reported at around 4.30pm on Wednesday.
The man, who was driving the Volkswagen, was taken to hospital by air ambulance.
The road was closed for around eight hours as a result before being reopened just after midnight.
Police are now appealing for information.
Sergeant Lloyd Caven, of Dumfries and Galloway Road Policing Unit, said: “Our thoughts go out to the family and friends of those involved with this tragic incident.
“Our inquiries are ongoing into the exact circumstances surrounding the crash and we would ask that if anyone was in the area at the time of the incident that they contact officers.
“I would also ask that if anyone has any possible dashcam footage of the area to get in touch with police.
“Anyone with information can contact police on 101.”