Rangers is helping police identify any season tickets holders who took part in anti-Irish Catholic singing in Glasgow on Sunday.
The club said it condemned “all forms of racism, sectarianism and discrimination” in a statement released on Monday night.
Footage on social media shows Rangers fans being escorted by police through Glasgow city centre ahead of Sunday’s Old Firm match chanting an anti-Irish song referencing the famine.
Police Scotland’s assistant chief constable Bernard Higgins said a “retrospective investigation” had been launched into the incident with “a number of arrests” expected to be made.
A Rangers Football Club statement read: “As a club, we are proud of our Everyone Anyone campaign, led through the Rangers Charity Foundation, our work with a wide range of stakeholders and our on-going dialogue with the Scottish Government.
“Discrimination of all forms is a societal issue within Scotland. Those with influence within Scottish discourse should put their energy into eradicating this very serious issue across all sections of Scottish society who suffer sectarianism, discrimination and racism of any form.”