The Old Firm game will kick-off at 3pm on Sunday after the Rangers and Celtic match was rescheduled to avoid clashing with Duke of Edinburgh’s funeral.
The Scottish Football Association said the change of plans was made following the announcement that Prince Philip’s funeral will take place at 3pm on Saturday, April 17.
All the Scottish Cup Fourth Round fixtures scheduled for the date have been changed.
Rangers versus Celtic was due to kick-off at 4pm on Saturday.
St. Mirren versus Inverness Caledonian and Motherwell versus Greenock Morton will be played on Friday night.
Kilmarnock versus Montrose will kick-off at 11.45am on Saturday, to ensure any extra time and penalties do not overlap with the Duke of Edinburgh’s funeral ceremony.
A Scottish FA spokesperson said: “In cognisance of the funeral ceremony of HRH Prince Philip this Saturday, April 17, the Scottish FA can now confirm revised kick-off times for the weekend’s Scottish Cup fourth-round ties.
“These amendments have been made in consultation with broadcast partners, relevant government officials, Police Scotland and participating clubs.”