New treatments for eye, blood and bladder cancers approved by NHS

The SMC backed the use of three new drugs on the NHS in Scotland

New treatments for eye, blood and bladder cancers approved by NHS ScotlandiStock

New cancer treatments have been approved for use by the NHS in Scotland – including the first licensed treatment for a rare eye cancer that offers patients a “survival benefit”.

The Scottish Medicines Consortium (SMC) backed the use of the drug tebentafusp – also known as Kimmtrak – for patients with advanced uveal melanoma, a rare type of cancer of the eye.

SMC chair Dr Rob Peel said the drug was “the first licensed treatment available for advanced uveal melanoma that offers a survival benefit”.

He added: “We know our decision will be welcomed by patients and their families.”

The SMC also approved the drug glofitamab – also known as Columvi – when used with other treatments for adults with diffuse large B‑cell lymphoma, a type of blood cancer.

The new drug can be used when patients have relapsed, or have not responded to other treatments, and where they can not have a stem cell transplant.

Dr Peel said it offered “improved survival outcomes” for those with the disease and who cannot have a transplant “compared with currently available treatments”.

In addition, the drug durvalumab – also known as Imfinzi – was approved for use, along with other medications and surgery, for adults with bladder cancer that has spread into the muscle layer.

Dr Peel said: “Adding durvalumab to the current treatment for bladder cancer that has spread into the muscle layer offers survival benefits.”

However, the committee said it had not recommended the drug avapritinib – also known as Ayvakyt – for use on the NHS to treat adults with advanced systemic mastocytosis.

Those suffering from the condition have too many abnormal white blood cells, but Dr Peel said: “The company’s evidence around the cost effectiveness of the treatment compared with other options was not sufficient.”

He added the SMC would “welcome a resubmission from the company addressing the issues we have raised”.

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