The Scotch Whisky Association (SWA) has stepped up calls for a further 2% cut in excise duty in the March Budget.
It said new figures demonstrated the drink is the biggest net contributor to UK trade in goods.
Exports are worth almost £4bn, while imports such as packaging for products and casks for maturing the spirit are £200m, giving the industry a trade balance of £3.8bn.
SWA said the UK’s trade deficit of almost £35bn would be 11% larger without the contribution of the industry.
In 2015, chancellor George Osborne announced a 2% cut, a year after a spirits duty freeze and scrapping of the alcohol escalator in 2014.
The industry said despite the improvement, tax on an average-priced bottle of whisky still stands at an “onerous” 76%.
David Frost, SWA chief executive, said: “These figures re-emphasise how significant the Scotch whisky industry is to the Scottish and wider UK economy, adding more than £5bn of value and supporting around 40,000 jobs.
“But it may surprise some people that Scotch whisky is now the number one contributor to the UK’s balance of trade in goods and that the trade deficit would be 11% higher without whisky exports.
“Given the scale and impact of the Scotch whisky industry, we believe the Government should redouble its efforts to support distillers.
“At home, in the short term, a further 2% duty cut in next month’s Budget would be a major boost, supporting small businesses that rely on the home market and further investment in the sector.”