Flybe have confirmed that they are stopping services between Aberdeen and Gatwick from next month.
Flybe took over the service from British Airways in 2008.
However the airline has decided to drop the route “after much consideration”.
A Flybe spokesman said: “Flybe carefully reviews the viability of all our 180 plus routes on a regular basis looking not only at passenger numbers but also at external cost pressures.
“This is done not only to monitor where we can offer increased regularity on a given route but also where passenger numbers make a flight environmentally, as well as economically, harder to justify.
“Unfortunately, after much consideration Flybe can confirm it is cancelling Aberdeen to Gatwick route from the end of the IATA summer season on Sunday, October 28.”
Last month Virgin announced it is planning to roll out services from Aberdeen to Heathrow next year.