A 62-year-old woman who had swine flu has become the tenth person to die in Scotland with the virus.
The Scottish Government said the woman, who was from the Forth Valley area, had significant underlying health conditions.
Health Secretary Nicola Sturgeon said: "Our thoughts are with the patient's family and friends, and I'd like to send my sincere condolences to her loved ones at this very sad time.
"As we have seen in previous cases, this patient was suffering from underlying health conditions and her death should not cause alarm among the general population.
"Fortunately in the vast majority of H1N1 cases, most people have fairly mild symptoms and make a full recovery within a week. But it's important that you get the help you need as quickly as possible if you are at greater risk."
Meanwhile, the number of people thought to have swine flu in Scotland has almost doubled in the past week. Health officials on Thursday said an estimated 13,800 people caught the H1N1 bug last week compared with about 7,000 the previous week.
Ms Sturgeon added: "H1N1 is now really becoming the predominant strain of flu that's circulating in Scotland. That very much mirrors the experience of Australia for their winter season when H1N1 was the main strain of flu that they were dealing with."
The total was based on data from 732 GP practices - equal to 71% of Scotland's total. Previously, the Scottish Government's weekly updates were based on 58 practices.
Scotland's Chief Medical Officer, Harry Burns, said swine flu was "elbowing out" seasonal flu. On the new figures, he said: "It's a significant sign that the H1N1 virus is filling a kind of ecological niche.
"But it's very important that we continue with the seasonal flu vaccination, because if this virus is affecting young people, seasonal flu tends to affect old people - we need to make sure both of them are protected. We need to get both vaccination programmes going to make sure we are not hit by both viruses at either end of the spectrum."
Speaking at St Andrew's House in Edinburgh on Thursday, Ms Sturgeon concluded: "We are not unique here - the increases that we are seeing this week, which build on a steady increase over the last three or four weeks, are being mirrored in all other parts of the UK.
"Northern Ireland has seen an even more dramatic increase this week - their consultation rates are now above 200 per 100,000."
The Health Secretary also confirmed that a patient from Lanarkshire, who had been sent for specialist treatment in England was now being treateed in Glasgow Royal Infirmary. The patient underwent a specialist procedure called extra corporeal membrane oxygenation (Ecmo) where blood is circulated outside the body and oxygen added artificially.
Lindy Paterson, who is in hospital in Ibiza with swine flu, is "making good progress".
Ms Sturgeon said the European Commission has now licensed the GSK vaccine - one of two which will be used in the UK. This will start to be delivered over the next few weeks, putting Scotland on track for its planned vaccination programme later this month.
